Which two derivatives of estradiol are commonly used as oral contraceptives?

Ethinyl estradiol and mestranol are commonly used as oral contraceptives due to their effectiveness in preventing ovulation and regulating menstrual cycles. Ethinyl estradiol is a modified form of estradiol that has enhanced oral bioavailability and potency, making it a popular choice in many contraceptive formulations. Mestranol is another synthetic derivative of estradiol which is converted to ethinyl estradiol in the body, serving a similar purpose in contraceptive use.

Other options presented do not fit the context of oral contraceptives. Estrone and estriol, while they are estrogens, are not commonly used in contraceptive formulations. Progesterone and norethindrone are progestins, which play a role in contraceptives but do not meet the requirement of being derivatives of estradiol. Daunorubicin and doxorubicin are both chemotherapy agents unrelated to contraceptive methods. Thus, the focus on ethinyl estradiol and mestranol highlights their significant role in hormonal birth control.